胺氧化酶

英文名稱：PAO；Plasma Amine Oxidase

CAS號：9001-66-5

級別：BR

來源：Bovine Plasma

Specific activity：≥17Tabor units/mg

活力定義：1 international unit oxidizes 1μmole of benzylamine perminute at 25℃, pH 7.2

催化反應：

產品描述：Bovine plasma amine oxidase has a molecular weight of 170 kDaand an optimum pH of 6.2 for spermine and 7.2 for spermidine. Amine oxidasesare divided into two classes: the pyridoxal and copper containing enzyme towhich plasma amine oxidase belongs, and the FAD-containing amino oxidases.Natural substrates include catecholamines, tryptamine derivatives and otherphysiologically active amines. Plasma amine oxidase is used in researchrequiring nitrogen group transfers. The molecule is composed of two identicalpolypeptide chains. There are two pyridoxal phosphates and two atoms of Cu+ permolecule. Bovine plasma amine oxidase is inhibited by copper chelating agents,many carboxyl reagents such as cuprizone, hydroxylamine and cyanide. Benzoicacid and benzyl alcohol are both non-competitive inhibitors (KI = 30 and 34mMrespectively). The assay for determination of amine oxidases employed atWorthington is essentially that of Tabor et al., JBC, 208, 645, (1954) with thereaction temperature reduced to 25℃

性狀(以下信息僅供參考)：粉末。EC3.1.1.4

用途：本品僅供科研，不得用于其它用途

保存：-20℃