產品屬性：
產品名稱 | C16 Ceramide (d18:1/16:0) |
規格 | 1mg、5mg、10mg、25mg |
貨號 | EY-01Y9604 |
Cas No.: 24696-26-2
別名: Palmitoyl Ceramide
化學名: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-hexadecanamide
分子式: C34H67NO3
分子量: 537.9
溶解度: 0.5mg/mL in DMF
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires coordinate action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence.[1] C16 ceramide (d18:1/16:0) is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling. [2] Accumulation of C16 ceramide (d18:1/16:0) through PPMP (30 μM) or MAPP (50 μM) treatment or from addition of 100 μM synthetic C16 ceramide (d18:1/16:0) induces apoptosis in neutrophil cultures via caspase-3 activation.[3]
特別提醒公司產品僅供科研使用
