產品屬性：
產品名稱 | Chloramphenicol succinate sodium |
規格 | 10mM*1 mL in DMSO、500mg |
貨號 | EY-01Y9619 |
Cas No.: 982-57-0
別名: N/A
化學名: N/A
分子式: C15H15Cl2N2NaO8
分子量: 445.18
溶解度: DMSO: 250 mg/mL (561.57 mM)
儲存條件: -20°C, protect from light, stored under argon
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Chloramphenicol succinate sodium is a prodrug of Chloramphenicol, with Haemotoxicity. Chloramphenicol succinate is a competitive substrate and inhibitor of succinate dehydrogenase (SDH) that is the possible reason for its toxicity[1][2][3].[1]. Ambrose PJ. Clinical pharmacokinetics of chloramphenicol and chloramphenicol succinate. Clin Pharmacokinet. 1984 May-Jun;9(3):222-38.
[2]. Ambekar CS, et al. Chloramphenicol succinate, a competitive substrate and inhibitor of succinate dehydrogenase: possible reason for its toxicity. Toxicol In Vitro. 2004 Aug;18(4):441-7.
[3]. Turton JA, et al. Haemotoxicity of chloramphenicol succinate in the CD-1 mouse and Wistar Hanover rat. Hum Exp Toxicol. 1999 Sep;18(9):566-76.
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