產品屬性：
產品名稱 | Chlorphenesin |
規格 | 10mM*1 mL in DMSO、25mg |
貨號 | EY-01Y9907 |
Cas No.: 104-29-0
別名: N/A
化學名: N/A
分子式: C9H11ClO3
分子量: 202.63
溶解度: DMSO: 100 mg/mL (493.51 mM)
儲存條件: 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Chlorphenesin is a reversible antigen-associated immunosuppressant. Chlorphenesin is an antibacterial and antifungal agent used in numerous eye care cosmetics[1].Chlorphenesin (0.01, 0.1, 0.3%; 30-min exposure) significantly reduces the activity of the Akt pathway in a dose-dependent manner in human meibomian gland epithelial cells (HMGECs)[2]. Chlorphenesin (0.1, 0.3%; 24 hours) induces immortalized HMGECs (IHMGECs) rounding, atrophy, poor adherence, detachme and significantly reduces the number of IHMGECs[2].[1]. H Y Whang, et al. Chlorphenesin: an antigen-associated immunosuppressant. Infect Immun. 1970 Jul;2(1):60-4.[2]. Jingyi Wang, et al. Toxicity of the cosmetic preservatives parabens, phenoxyethanol and chlorphenesin on human meibomian gland epithelial cells. Exp Eye Res. 2020 Jul;196:108057."
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