產品屬性：
產品名稱 | Cloxacillin (sodium salt) |
規格 | 5g、10g、25g |
貨號 | EY-01Y9877 |
Cas No.: 642-78-4
別名: N/A
化學名: N/A
分子式: C19H17ClN3O5S?Na
分子量: 457.9
溶解度: DMF: 20 mg/ml,DMSO: 16 mg/mL,Ethanol: 2 mg/mL,PBS (pH 7.2): 10 mg/mL
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Cloxacillin is a semisynthetic β-lactamase inhibitor. It binds to and inactivates penicillin-binding proteins that cross-link peptidoglycans, which are structural components of bacterial cell walls. In vitro, addition of cloxacillin (0.50 μg/ml) almost completely inhibits B. megaterium growth. Cloxacillin inhibits recombinant type Ib penicillinase, P. vulgaris cephalosporinase, and C. freundii cephalosporinase (Kis = 15, 0.27, and 0.027 μM, respectively) as well as S. aureus and S. epidermidis growth (MICs = 0.2 and 0.2 μg/ml, respectively). In vitro, addition of cloxacillin (0.50 μg/ml) almost completely inhibits B. megaterium growth. Formulations containing cloxacillin have been used to treat infections caused by methicillin-sensitive staphylococci.
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