產品屬性：

Cas No.: 25953-19-9

別名: N/A

化學名: N/A

分子式: C14H14N8O4S3

分子量: 454.51

溶解度: DMSO: 250 mg/mL (550.04 mM)

儲存條件: 4°C, away from moisture
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

產品描述：

Cefazolin is an antibiotic used for the research of a number of anti-bacterial infections. Cefazolin can be used for the prophylaxis of surgical antimicrobial.   Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD)[1].Cefazolin (50-300 μg/mL; 6 or 24 hours) has a direct anti-inflammatory effect on C8-B4 cells stimulated by LPS (1 μg/mL)[1]. Cell Viability Assay[1] Cell Line:    Mouse C8-B4 microglial cellsCefazolin (300 mg/kg; injected intraperitoneally 1 h before surgery and then once per day for 5 days after surgery) can attenuate surgery-induced post-operative memory and learning impairment in mice. Cefazolin alone may induce cognitive dysfunction possibly by transient gut dysbiosis in mice without surgery[1].    Animal Model:Six- to 8-week-old CD-1 male mice (weighing 31-36 g) [1][1]. Peng Liang, et al.   Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice. J Neuroinflammation. 2018 Aug 22;15(1):235.
特別提醒公司產品僅供科研使用