產品屬性：
產品名稱 | STING Agonist 12b |
規格 | 500 μg、1 mg、5 mg、10 mg |
貨號 | EY-01Y10564 |
Cas No.: 2411100-70-2
別名: N/A
化學名: N/A
分子式: C16H15NO2
分子量: 253.3
溶解度: DMF: 1 mg/ml,DMSO: 1 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1 It binds to STING (Kd = 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.1.Hou, S., Lan, X.-j., Li, W., et al.Design, synthesis and biological evaluation of acridone analogues as novel STING receptor agonistsBioorg. Chem.95103556(2020)
特別提醒公司產品僅供科研使用
