產品屬性：
產品名稱 | Complement C5-IN-1 |
規格 | 1mg、5mg、10mg、50mg |
貨號 | EY-01Y10624 |
Cas No.: 2365402-67-9
別名: N/A
化學名: N/A
分子式: C24H32N2O6
分子量: 444.52
溶解度: DMSO: ≥ 100 mg/mL (224.96 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Complement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein (C5). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC50 of 0.77 μM[1].[1]. Jendza K, et al. A small-molecule inhibitor of C5 complement protein. Nat Chem Biol. 2019 Jul;15(7):666-668.
特別提醒公司產品僅供科研使用
