產品屬性：
產品名稱 | C-170 |
規格 | 10 mg、25 mg、50 mg、100 mg |
貨號 | EY-01Y10749 |
Cas No.: 346691-38-1
別名: N/A
化學名: N/A
分子式: C15H16N2O4
分子量: 288.3
溶解度: DMSO: Soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
C-170 is an inhibitor of stimulator of interferon genes (STING).1,2 It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.1 It selectively reduces human and mouse STING-, but not RIG-I- or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 μM.1.Haag, S.M., Gulen, M.F., Reymond, L., et al.Targeting STING with covalent small-molecule inhibitorsNature559(7713)269-273(2018)
2.Zhang, H., You, Q.-D., and Xu, X.-L.Targeting stimulator of interferon genes (STING): A medicinal chemistry perspectiveJ. Med. Chem.63(8)3785-3816(2019)
特別提醒公司產品僅供科研使用
