產品屬性：
產品名稱 | Argatroban monohydrate |
規格 | Free Sample (0.1-0.5 mg)、10mM*1mL in DMSO、10mg、50mg、100mg、200mg、500mg |
貨號 | EY-01Y11037 |
Cas No.: 141396-28-3
別名: N/A
化學名: N/A
分子式: C23H38N6O6S
分子量: 526.65
溶解度: DMSO: ≥ 100 mg/mL (189.88 mM); H2O: < 0.1 mg/mL (insoluble)
儲存條件: 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Argatroban (monohydrate) (MD-805 (monohydrate)) is a direct, selective thrombin inhibitor.Thrombin[1].Argatroban (MD-805) may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of Argatroban (MD-805) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries[1]. Argatroban (MD-805), as compared with heparin, appears to enhance reperfusion with TPA in patients with AMI, particularly in those patients with delayed presentation. The incidences of major bleeding and adverse clinical outcome were lower in the patients receiving argatroban[2].[1]. Kawada, T., et al., Argatroban, an attractive anticoagulant, for left heart bypass with centrifugal pump for repair of traumatic aortic rupture. Jpn J Thorac Cardiovasc Surg, 1999. 47(3): p. 104-9.
[2]. Jang, I.K., et al., A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol, 1999. 33(7): p. 1879-85.
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