產品屬性：
產品名稱 | Cyclic AMP |
規格 | 500mg、1g、5g |
貨號 | EY-01Y11306 |
Cas No.: 60-92-4
別名: N/A
化學名: N/A
分子式: C10H12N5O6P
分子量: 329.21
溶解度: insoluble in DMSO; insoluble in EtOH; >16.45 mg/mL in H2O
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Cyclic adenosine 3', 5'-monophosphate (cAMP) was the first second messenger to be identified, with the IC50 of LPA- or EGF-stimulated ERK1 was 0.1-0.2 Mm [1].
Ras is a common target for growth factors including epidermal growth factor (EGF) and lysophosphatidic acid (LPA), which activate the Raf-MEK-ERK pathway. Raf is likely to be a link between Ras and ERK cascade, of which Raf-1activates MEK in vitro.
Quiescent Rat1 cells were incubated with 1 Mm dibutyryl cAMP for 10 min before stimulation with LPA or EGF, ERK activation was completely inhibited by protein immunoblots. The ability of the phorbol ester PMA to activate MAP kinase was also inhibited by dibutyryl cAMP [1].
特別提醒公司產品僅供科研使用
