產品屬性：
產品名稱 | Amobarbital (sodium salt) |
規格 | 1 mg、5 mg |
貨號 | EY-01Y11455 |
Cas No.: 64-43-7
別名: N/A
化學名: N/A
分子式: C11H17N2O3.Na
分子量: 248.3
溶解度: DMF: 0.3 mg/ml,DMSO: 0.5 mg/ml,PBS (pH 7.2): 0.3 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Amobarbital (sodium salt) is an analytical reference standard that is categorized as a barbiturate. By activating GABAA receptors in rat thalamic slices, 100 μM amobarbital elicits a depressant effect, increasing both the amplitude and decay time of inhibitory postsynaptic currents.1 It has also been shown to compete with rotenone for binding at complex I to inhibit mitochondrial electron transport.2 Amobarbital is regulated as a schedule II compound in the United States and intended only for forensic and research purposes.1.Kim, H.S., Wan, X., Mathers, D.A., et al.Selective GABA-receptor actions of amobarbital on thalamic neuronsBr.J.Pharmac.143(4)485-494(2004)
2.Chen, A., Hoppel, C.L., and Lesnefsky, E.J.Blockade of electron transport before cardiac ischemia with the reversible inhibitor amobarbital protects rat heart mitochondriaJournal of Pharmacology and Experimental Therapeutics316(1)200-207(2006)
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