產品屬性：
產品名稱 | D-Glucose-6-phosphate (sodium salt) |
規格 | 500mg、1g、5g |
貨號 | EY-01Y11573 |
Cas No.: 54010-71-8
別名: G6P, Sodium Glucose-6-Phosphate
化學名: sodium ((2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)methyl hydrogenphosphate
分子式: C6H12NaO9P
分子量: 282.12
溶解度: 10mg in PBS， pH 7.2
儲存條件: Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
D-Glucose-6-phosphate is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or by the conversion of glucose-1-phosphate by phosphoglucomutase, which is the first step of glycogen synthesis.[1] It is stored as glycogen when blood glucose levels are high. Disruption of D-glucose-6-phosphate activity leads to glycogen storage disease type I or von Gierke’s disease, a group of inherited metabolic diseases characterized by severe hypoglycemia, growth retardation, and hepatomegaly, due to accumulation of glycogen and fat in the liver.[2],[3] D-Glucose-6-phosphate is also the starting molecule of both glycolysis and the pentose phosphate pathways.[4] Because cancer cells adopt glycolysis as a major source of metabolic energy production, and the pentose phosphate pathway plays a role in helping glycolytic cancer cells to meet their anabolic demands, this compound can be used to study the progression of this process.[5]
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