產品屬性：
產品名稱 | CTPI-2 |
規格 | 5mg、10mg、25mg |
貨號 | EY-01Y11704 |
Cas No.: 68003-38-3
別名: N/A
化學名: 2-((4-chloro-3-nitrophenyl)sulfonamido)benzoic acid
分子式: C13H9CIN2O6S
分子量: 356.74
溶解度: DMSO:125 mg/mL(350.40 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
CTPI-2 (SLC25A1 inhibitor CTPI-2) is a novel specific SLC25A1 inhibitor with Kd of 3.5 uM, CTPI-2 is synthetic lethal with cisplatin or with EGFR inhibitor co-treatment and restores antitumor responses both in vitro and in vivo; disrupts self-renewal and sphere-forming capacity of the indicated tumor cells relative to monolayer cultures, demonstrates broad activity on lung CSCs, inhibiting mitochondrial respiratory activity, self-renewal and matrix invasion; inhibits tumor growth in in vivo models of NSCLC.
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