產品屬性：
產品名稱 | Fibronectin Adhesion-promoting Peptide |
規(guī)格 | 1mg、5mg、10mg |
貨號 | EY-01Y12016 |
Cas No.: 125720-21-0
別名: N/A
化學名: N/A
分子式: C47H74N16O10
分子量: 1023.19
溶解度: H2O: 2 mg/mL (1.95 mM and warming)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Heparin Binding Peptide is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin.GRGDS and Heparin Binding Peptide (WQPPRARI peptide) micropatterns increase the endothelialisation of prosthetic materials in vitro. WQPPRARI peptide also enhances haptotactic cell migration. The anti-apoptotic effects of fibronectin require the presence of the WQPPRARI sequence, which may be due to synergistic survival signals mediated by this sequence and by the RGD motif[1]. RDGS and WQPPRARI peptides promote cell adhesion through different activation pathways that induce different forms of adhesion which can be highlighted through the analysis of focal and fibrillar contacts[2].[1]. Hoesli CA, et al. A fluorophore-tagged RGD peptide to control endothelial cell adhesion to micropatterned surfaces. Biomaterials. 2014 Jan;35(3):879-90.
[2]. Chollet C, et al. Impact of peptide micropatterning on endothelial cell actin remodeling for cell alignment under shear stress. Macromol Biosci. 2012 Dec;12(12):1648-59.
特別提醒公司產品僅供科研使用
