產品屬性：
產品名稱 | DC_C66 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y12533 |
Cas No.: 108181-00-6
別名: N/A
化學名: N/A
分子式: C28H22NO2+
分子量: 404.48
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
DC_C66 is a cell-permeable, selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 1.8 μM. DC_C66 has a good selectivity for CARM1 against PRMT1 (IC50=21 μM), PRMT6 (IC50= 47μM), and PRMT5[1].IC50: 1.8 μM (CARM1)[1]DC_C66 (6.25-100 μM; 24-72 hours) exhibits antiproliferation activity in several CARM1-associated cancer cell lines[1].Cell Proliferation Assay[1] Cell Line:HELA, K562, MCF7 cells[1]. Ye F, et al. Identification of Novel Inhibitors against Coactivator Associated Arginine Methyltransferase 1 Based on Virtual Screening and Biological Assays. Biomed Res Int. 2016;2016:7086390.
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