產品屬性：
產品名稱 | CAY10727 |
規格 | 100 μg、250 μg、500 μg、1 mg |
貨號 | EY-01Y12596 |
Cas No.: 1671088-84-8
別名: N/A
化學名: N/A
分子式: C21H22Cl2N4O2
分子量: 433.3
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
CAY10727 is an inhibitor of protein arginine deiminase 3 (PAD3; kinact/KI = 15,600 M-1min-1).1 It is selective for PAD3 over PAD1, -2, and -4 (kinact/KIs = 360, 1,110, and 1,460 M-1min-1, respectively).1.Jamali, H., Khan, H.A., Stringer, J.R., et al.Identification of multiple structurally distinct, nonpeptidic small molecule inhibitors of protein arginine deiminase 3 using a substrate-based fragment methodJ. Am. Chem. Soc.137(10)3616-3621(2015)
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