產品屬性：
產品名稱 | ALK-IN-5 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y12781 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C24H25FN6O3
分子量: 464.49
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9 nM[1].IC50: 2.9 nM (ALK)[1]ALK-IN-5 potently inhibits ALK with cellular IC50 of 27 nM[1].[1]. Fushimi M, et al. Discovery of Potent, Selective, and Brain-Penetrant 1 H-Pyrazol-5-yl-1 H-pyrrolo[2,3- b]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors. J Med Chem. 2019 May 23;62(10):4915-4935.
特別提醒公司產品僅供科研使用
