產品屬性：
產品名稱 | Bilobetin |
規格 | 1mg、5mg |
貨號 | EY-01Y12767 |
Cas No.: 521-32-4
別名: N/A
化學名: N/A
分子式: C31H20O10
分子量: 552.48
溶解度: DMF: 10mg/mL,DMSO: 25mg/mL,DMSO:PBS (pH 7.2) (1:6): 0.14mg/mL,Ethanol: 2.5mg/mL
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity[1].
PPARα PKA
[1]. Kou XH, et al. Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet. Br J Pharmacol. 2012 Apr;165(8):2692-706.
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