產(chǎn)品屬性：
產(chǎn)品名稱 | Rp-8-bromo-Cyclic AMPS (sodium salt) |
規(guī)格 | 500μg、1mg、5mg |
貨號(hào) | EY-01Y12745 |
Cas No.: 925456-59-3
別名: N/A
化學(xué)名: N/A
分子式: C10H10BrN5O5PS ?Na
分子量: 446.1
溶解度: DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 0.5 mg/ml,PBS (pH 7.2): 10 mg/ml
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.
特別提醒公司產(chǎn)品僅供科研使用
