產品屬性：
產品名稱 | CHMFL-KIT-033 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y12829 |
Cas No.: 2351801-41-5
別名: N/A
化學名: N/A
分子式: C23H18FN5O2
分子量: 415.42
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
CHMFL-KIT-033 is a potent and selective inhibitor of c-KIT T670I mutant for gastrointestinal stromal tumors (GISTs), with an IC50 of 0.045 μM[1].IC50: 0.045 μM (c-KIT T670I mutant)[1][1]. Liu X, et al. Discovery of ( E)- N1-(3-Fluorophenyl)- N3-(3-(2-(pyridin-2-yl)vinyl)-1 H-indazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs). J Med Chem. 2019 May 23;62(10):5006-5024.
特別提醒公司產品僅供科研使用
