產品屬性：
產品名稱 | Aldehyde Reactive Probe (trifluoroacetate salt) |
規格 | 5mg、10mg、25mg、50mg |
貨號 | EY-01Y12931 |
Cas No.: 627090-10-2
別名: N/A
化學名: N/A
分子式: C12H21N5O4S?CF3COOH
分子量: 445.4
溶解度: DMF: 20 mg/ml,DMSO: 15 mg/ml,PBS (pH 7.2): 3 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
DNA is continually damaged by endogenous and environmental agents leading to the formation of abasic (apurinic/apyrimidinic, AP) sites that are disruptive to DNA synthesis. Aldehyde Reactive Probe (ARP) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA. ARP reacts with aldehyde groups formed when reactive oxygen species depurinate DNA, resulting in covalent linkage of biotin to these AP sites. The biotin-tagged DNA can then be detected using common avidin-conjugated reporters such as avidin-HRP. The ARP method is highly sensitive, enabling detection of 2.4 AP sites per 1x107 nucleotides of DNA.
特別提醒公司產品僅供科研使用
