產品屬性:
產品名稱 | BRCA1-IN-2 |
規格 | 100mg、250mg、500mg |
貨號 | EY-01Y13159 |
Cas No.: 1622262-55-8
別名: N/A
化學名: N/A
分子式: C26H33N4O7P

分子量: 544.54
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions[1].IC50: 0.31 μM (BRCA1)[1]Kd: 0.3 μM (BRCA1)[1][1]. Na Z, et al. Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays. Methods Mol Biol. 2017;1518:139-156.
特別提醒公司產品僅供科研使用