產品屬性：
產品名稱 | ARN24139 |
規格 | 1 mg、5 mg、10 mg |
貨號 | EY-01Y13183 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C24H16F3N3O4S
分子量: 499.5
溶解度: DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml,DMSO: 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
ARN24139 is a topoisomerase II poison (IC50 = 7.3 μM in a topoisomerase II decatenation assay).1 It inhibits proliferation of DU145, HeLa, and A549 cells (IC50s = 4.7, 3.8, and 3.1 μM, respectively).1.Arencibia, J.M., Brindani, N., Franco-Ulloa, S., et al.Design, synthesis, dynamic docking, biochemical characterization, and in vivo pharmacokinetics studies of novel topoisomerase II poisons with promising antiproliferative activityJ. Med. Chem.63(7)3508-3521(2020)
特別提醒公司產品僅供科研使用
