產品屬性：
產品名稱 | Amyloid Precursor C-Terminal Peptide |
規格 | 1mg、5mg、10mg、25mg |
貨號 | EY-01Y13322 |
Cas No.: N/A
別名: H2N-Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn-OH
化學名: N/A
分子式: C86H118N20O27S1
分子量: 1896.04
溶解度: ≥ 189.6mg/mL in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Amyloid precursor c-terminal peptide (APP) (C86H118N20O27S) has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. Although it has been implicated as a regulator of synapse formation, neural plasticity and iron export, the primary function of APP is not known. APP is best known as the precursor molecule whose proteolysis generates beta amyloid (A?), a 37 to 49 amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. So it is a possible contributor to Alzheimer¤s pathogenesis through MAPKs- and NF-?B-dependent astrocytosis. Recently, APP origin was demonstrated with arthritogenic animals. Also, it induces secondary inflammation, which may cause local damage.
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