產品屬性:
產品名稱 | Beta-Sheet Breaker Peptide iAβ5 |
規格 | 5mg、10mg、25mg |
貨號 | EY-01Y13372 |
Cas No.: 182912-74-9
別名: H2N-Leu-Pro-Phe-Phe-Asp-OH
化學名: N/A
分子式: C33H43N5O8

分子量: 637.73
溶解度: ≥ 63.7mg/mL in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Beta-Sheet Breaker Peptide iAβ5 (C33H43N5O8), with the sequence H-Leu-Pro-Phe-Phe-Asp-OH, has been shown to inhibit amyloidogenesis in rat brain models. Research showed that beta-sheet breaker peptide significantly reduces amyloid beta-protein deposition in vivo and completely blocks the formation of amyloid fibrils in a rat brain model of amyloidosis. Current evidence supports the notion that beta-amyloid deposits or Abeta intermediates may be responsible for the pathogenesis in Alzheimer’s disease (AD) patients. Because of its inhibition of cerebral amyloid beta-protein deposition, Beta-Sheet Breaker Peptide seems to be an important target for Alzheimer's disease therapy.
特別提醒公司產品僅供科研使用