產品屬性：
產品名稱 | Benastatin C |
規格 | 1 mg |
貨號 | EY-01Y13547 |
Cas No.: 150151-88-5
別名: N/A
化學名: N/A
分子式: C29H28O5
分子量: 456.5
溶解度: N/A
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Benastatin C is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities.1,2 It inhibits glutathione S-transferase (GST; IC50 = 24 μg/ml for the rat liver enzyme).2 Benastatin C also inhibits the esterase activity of isolated porcine pancreatic lipase (IC50 = 10 μg/ml). It increases LPS- or concanavalin A-induced blastogenesis of isolated mouse spleen lymphocytes in a concentration-dependent manner.1.Xu, Z., Schenk, A., and Hertweck, C.Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybridsJ. Am. Chem. Soc.129(18)6022-6030(2007)
2.Aoyama, T., Kojima, F., Yamazaki, T., et al.Benastatins C and D, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activitiesJ. Antibiot. (Tokyo)46(5)712-718(1993)
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