產品屬性：
產品名稱 | C82 |
規格 | 1 mg、5 mg、10 mg |
貨號 | EY-01Y13562 |
Cas No.: 691862-35-8
別名: N/A
化學名: N/A
分子式: C17H17N3O3S
分子量: 343.4
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
C82 is an inhibitor of M. tuberculosis (Mtb) cyclic dinucleotide phosphodiesterase (CdnP; IC50 = 17.5 μM), the enzyme that catalyzes the hydrolysis of cyclic di-AMP to adenosine 5’-monophosphate .1 It is selective for Mtb CdnP over the additional bacterial CDN phosphodiesterases (PDEs) Yybt, RocR, and group B streptococcus (GBS) CdnP, the mammalian CDN PDE ENPP1, and the viral CDN PDE poxin at 200 μM.1.Karanja, C.W., Yeboah, K.S., and Sintim, H.O.Identification of a Mycobacterium tuberculosis cyclic dinucleotide phosphodiesterase inhibitorACS Infect. Dis.7(2)309-317(2021)
特別提醒公司產品僅供科研使用
