產品屬性：
產品名稱 | BI-2545 |
規格 | 5mg、10mg、25mg、50mg、100mg |
貨號 | EY-01Y13702 |
Cas No.: 2162961-71-7
別名: N/A
化學名: N/A
分子式: C23H19F6N5O3
分子量: 527.42
溶解度: DMSO: 250 mg/mL (474.01 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
BI-2545 is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC50s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively[1].BI-2545 displays good potency in the LPA and rat whole blood assay with IC50s of 29 nM and 96 nM, respectively[1].BI-2545 (10 mg/kg; p.o.) has high and sustained in vivo efficacy in reducing LPAs[1].BI-2545 (10 mg/kg; p.o.) has a half-life of t1/2=3.4 hours[1].
特別提醒公司產品僅供科研使用
