產品屬性:
產品名稱 | Concanamycin B |
規格 | 250μg、1mg |
貨號 | EY-01Y13907 |
Cas No.: 81552-33-2
別名: N/A
化學名: N/A
分子式: C45H73NO14

分子量: 852.1
溶解度: DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM). In this way, it blocks the acidification of vacuolar organelles as well as early to late endosomal transport. Concanamycin B interferes with bone resorption and maturation of CD8 T lymphocytes. It also prevents processing of major histocompatibility complex (MHC) class II precursors in human B cells, inhibiting the expression of MHC class II molecules on the cell surface.
特別提醒公司產品僅供科研使用