產品屬性：
產品名稱 | 7-Ethoxycoumarin |
規格 | 100 mg、250 mg、500 mg、1 g |
貨號 | EY-01Y14242 |
Cas No.: 31005-02-4
別名: N/A
化學名: N/A
分子式: C11H10O3
分子量: 190.2
溶解度: DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:1): 0.50 mg/ml,DMSO: 15 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
7-Ethoxycoumarin is a substrate for cytochrome P450 (CYP).1 It undergoes O-deethylation by various CYP isoforms, including CYP1A1, -1A2, and -2B in mice and CYP2E1 in humans. 7-Ethoxycoumarin has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea.2,3,41.Okamatsu, G., Komatsu, T., Kubota, A., et al.Identification and functional characterization of novel feline cytochrome P450 2AXenobiotica45(6)503-510(2015)
2.Kajbaf, M., Ricci, R., Zambon, S., et al.Contribution of rat intestinal metabolism to the xenobiotics clearanceEur. J. Drug Metab. Pharmacokinet.38(1)33-41(2013)
3.K?lln, C., and Reichl, S.Cytochrome P450 activity in ex vivo cornea models and a human cornea constructJ. Pharm. Sci.105(7)2204-2212(2016)
特別提醒公司產品僅供科研使用
