產品屬性：
產品名稱 | (±)-Atenolol-d7 |
規格 | 1 mg、5 mg、10 mg、25 mg |
貨號 | EY-01Y14227 |
Cas No.: 1202864-50-3
別名: N/A
化學名: N/A
分子式: C14D7H15N2O3
分子量: 273.4
溶解度: Chloroform: slightly soluble,Methanol: slightly soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
(±)-Atenolol-d7 is intended for use as an internal standard for the quantification of (±)-atenolol by GC- or LC-MS. (±)-Atenolol is an antagonist of the β1-adrenergic receptor (β1-AR; Ki = 1.14 μM).1 It is selective for β1-ARs over β2-ARs (Ki = 48.7 μM). (±)-Atenolol (200 mg/kg per day) delays the onset of hypertension in spontaneously hypertensive rats.2 Formulations containing atenolol have been used in the treatment of high blood pressure. 1.Golf, S., Bjornerheim, R., Erichsen, A., et al.Relative selectivity of different β-adrenoceptor antagonists for human heart β1- and β2-receptor subtypes assayed by a radioligand binding techniqueScand. J. Clin. Lab. Invest.47(7)719-723(1987)
2.Richer, C., Boissier, J.R., and Giudicelli, J.F.Chronic atenolol treatment and hypertension development in spontaneously hypertensive ratsEur. J. Pharmacol.47(4)393-400(1978)
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