產品屬性：
產品名稱 | Alloisolithocholic Acid |
規格 | 5 mg、10 mg、25 mg |
貨號 | EY-01Y14596 |
Cas No.: 2276-93-9
別名: AILCA
化學名: (5α)-3β-hydroxy-cholan-24-oic acid
分子式: C24H40O3
分子量: 376.6
溶解度: DMF: 1mg/mL,DMF:PBS (pH 7.2) (1:3): 0.25mg/mL
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Alloisolithocholic acid (AILCA) is an allomonohydroxy bile acid.[1],[2] It activates large-conductance calcium-activated potassium channels (BKCas; EC50 = 44.21 μM in Xenopus oocytes expressing human channels).[1] AILCA (6 mg/kg) reduces hepatic bile flow and bile salt, cholesterol, and phospholipid secretion, as well as induces loss of microvilli and dilation of canaliculi in hepatocytes, markers of cholestasis, in rats.[2]
特別提醒公司產品僅供科研使用
