產品屬性：
產品名稱 | 4’-hydroxy Trazodone |
規格 | 1 mg |
貨號 | EY-01Y14691 |
Cas No.: 53818-10-3
別名: N/A
化學名: N/A
分子式: C19H22ClN5O2
分子量: 387.9
溶解度: Chloroform: slightly soluble,Methanol: slightly, sonicated
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.1 It is an inhibitor of organic anion transporter 3 (OAT3; Ki = 16.9 μM) and is selective for OAT3 over OAT1 (Ki = >200 μM).2 1.Yamato, C., Takahashi, T., Fujita, T., et al.Studies on metabolism of trazodone, II. Metabolic fate after intravenous administration and effects on liver microsomal drug-metabolizing enzymes in ratsXenobiotica4(12)765-777(1974)
2.Zou, L., Matsson, P., Stecula, A., et al.Drug metabolites potently inhibit renal organic anion transporters, OAT1 and OAT3J. Pharm. Sci.110(1)347-353(2021)
特別提醒公司產品僅供科研使用
