產品屬性：
產品名稱 | Colchicoside |
規格 | 5 mg、10 mg、25 mg、50 mg |
貨號 | EY-01Y14755 |
Cas No.: 477-29-2
別名: N/A
化學名: N/A
分子式: C27H33NO11
分子量: 547.6
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Colchicoside is a glycoside form of 3-demethylcolchicine that has been found in G. superba.1 Unlike cholchicine and 3-demethylcolchicine, colchicoside does not displace [3H]-colchicine from rat brain tubulin in vitro when used at a concentration of 25 μM.2 Colchicoside (1 and 10 μM) increases levels of the cytochrome P450 (CYP) isoforms CYP2C9 and CYP2E1 in primary human hepatocytes.31.Capistrano, I.R., Vangestel, C., Vanpachtenbeke, H., et al.Coadministration of a Gloriosa superba extract improves the in vivo antitumoural activity of gemcitabine in a murine pancreatic tumour modePhytomedicine23(12)1434-1440(2016)
2.Sugio, K., Maruyama, M., Tsurufuji, S., et al.Separation of tubulin-binding and anti-inflammatory activity in colchicine analogs and congenersLife Sci.40(1)35-39(1987)
3.Dvorák, Z., Ulrichová, J., ModrianskY, M., et al.Effect of colchicine and its derivatives on the expression of selected isoforms of cytochrome P450 in primary cultures of human hepatocytesActa Univ. Palacki. Olomuc. Fac. Med.14347-50(2000)
特別提醒公司產品僅供科研使用
