產品屬性：
產品名稱 | 2-Aminopurine (hydrochloride) |
規格 | 50mg、100mg、250mg、500mg |
貨號 | EY-01Y14837 |
Cas No.: 1428126-74-2
別名: 2-AP
化學名: 9H-purin-2-amine, dihydrochloride
分子式: C5H5N5?2HCl
分子量: 208.1
溶解度: PBS (pH 7.2): 5 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
2-Aminopurine is a fluorescent analog of guanosine and adenosine that is used as a site-specific probe of nucleic acid structure and dynamics. It base pairs with cytosine in a wobble configuration or with thymine in a Watson-Crick geometry. [1] In addition to its usefulness in studies of base stacking interactions, 2-aminopurine has been used as a probe for DNA base flipping by methyl transferases. [2] 2-Aminopurine exhibits an excitation/emission of 320/381 nm, respectively, when adjusted to reduce interference with DNA base absorption as well as tryptophan fluorescence. 2-Aminopurine inhibits the double-stranded RNA-dependent protein kinase, protein kinase R, whose activity mediates antiviral defense and participates in toll-like receptor signaling.[3]
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