產品屬性：
產品名稱 | Betulonaldehyde |
規格 | 10mg、50mg、100mg |
貨號 | EY-01Y14792 |
Cas No.: 4439-98-9
別名: N/A
化學名: N/A
分子式: C30H46O2
分子量: 438.7
溶解度: DMF: 10 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Betulonaldehyde is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found in Betula.1 It is active against P. falciparum (IC50 = 3.36 μg/ml) and cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s = 19.23 and 17.09 μg/ml, respectively).2 Topical application of betulonaldehyde (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate in mice.3 It has also been used a precursor in the semisynthesis of C-2 and C-28 betulonic aldehyde derivatives.11.Ayers, S., Benkovics, T., Marshall, J., et al.Autoxidation products of betulonaldehydeJ. Nat. Prod.79(10)2758-2761(2016)
2.Wisetsai, A., Schevenels, F.T., and Lekphrom, R.Chemical constituents and their biological activities from the roots of diospyros filipendulaNat. Prod. Res.1-5(2019)
3.Yasukawa, K., Yu, S., Yamanouchi, S., et al.Some lupane-type triterpenes inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skinPhytomedicine1(4)309-313(1995)
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