產品屬性：
產品名稱 | α-Truxillic Acid |
規格 | 10mg、50mg、100mg、500mg |
貨號 | EY-01Y14938 |
Cas No.: 490-20-0
別名: Gratissimic Acid
化學名: (1α,2α,3β,4β)-2,4-diphenyl-1,3-cyclobutanedicarboxylic acid
分子式: C18H16O4
分子量: 296.3
溶解度: 20mg/mL in DMSO, 16mg/mL in DMF
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
α-Truxillic acid can be formed by the dimerization of two molecules of α-trans-cinnamic acid. [1] It is related to incarvillateine, a natural antinociceptive compound derived from the Asian herb I. sinensis. [2] α-Truxillic acid and some of its derivatives significantly block inflammatory pain while having little effect on neurogenic pain, as indicated by the formalin test in mice. [2] [3] Related compounds, like SB-FI-26 , bind fatty acid binding protein 5 (FABP5). [4] This may be related to pain suppression, since FABP5 acts as a transporter of the endocannabinoid anandamide. [5] While certain derivatives of α-truxillic acid can directly activate peroxisome proliferator-activated receptor γ, α-truxillic acid has no such activity. [6]
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