產品屬性:
產品名稱 | AF40431 |
規格 | 1mg、5mg、10mg、25mg、50mg、100mg、200mg、500mg |
貨號 | EY-01Y15065 |
Cas No.: 181125-92-8
別名: N/A
化學名: N/A
分子式: C17H21NO5

分子量: 319.35
溶解度: DMSO: 25 mg/mL (78.28 mM; ultrasonic and adjust pH to 1 with TFA)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 μM and a Kd of 0.7 μM . AF40431 is bound in the neurotensin-binding site of sortilin[1].[1]. Andersen JL, et al. Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):451-60.
特別提醒公司產品僅供科研使用