產品屬性：
產品名稱 | Biotin-NAD+ |
規格 | 131 ug |
貨號 | EY-01Y15635 |
Cas No.: 146385-37-7
別名: N/A
化學名: N/A
分子式: C39H57N11O17P2S
分子量: 1045.95
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Provides a convenient non-isotopic alternative to radiolabeled NAD+ for determination of IC50 values for candidate PARP inhibitors and studies requiring this substrate. Biotinylated-NAD+ allows an indirect measure of PARP activity when biotin incorporation is detected using a conjugated-streptavidin detection system. Acts as a substrate for ADP-ribosylation. Can be used to label and purify biotinyl-ADP ribosylated proteins. This product is a replacement for R&D Systems product 4670-500-01. 131 μg is supplied as 500 μl of a 0.25 mM solution in water.
Zhang et al (1993) Purification of a nitric oxide-stimulated ADP-ribosylated protein using biotinylated beta-nicotinamide adenine dinucleotide. Biochemistry 32 2228 PMID:8443164 |Yang et al (2017) Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9 Mol. Cell 66 613 PMID:28525742 |Schuster et al (2017) The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells. Sci.Rep. 7 613 PMID:28377614 |Yang (2013) Antitumor activity of a pyrrole-imidazole polyamide. Proc.Natl.Acad.Sci.USA 110 1863 PMID:23319609
特別提醒公司產品僅供科研使用
