產品屬性：
產品名稱 | Carbazeran |
規格 | 500μg、1mg、5mg、10mg |
貨號 | EY-01Y15678 |
Cas No.: 70724-25-3
別名: N/A
化學名: N/A
分子式: C18H24N4O4
分子量: 360.4
溶解度: Chloroform: Slightly Soluble,Methanol: Slightly Soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Carbazeran is an inhibitor of phosphodiesterase 2 (PDE2) and PDE3. It inhibits cAMP hydrolysis (IC50 = 4.1 μM in rabbit heart ventricles) selectively over cGMP hydrolysis (IC50 = 171 μM). It induces positive inotropic (EC50 = 100 μM) and negative chronotropic effects in isolated rabbit papillary muscle and right atria, respectively. Carbazeran is also a substrate for the enzyme aldehyde oxidase (AOX1), which is involved in the metabolism of xenobiotics.
特別提醒公司產品僅供科研使用
