產品屬性：
產品名稱 | BPC 157 (acetate) |
規格 | 1 mg、5 mg、10 mg、25 mg |
貨號 | EY-01Y16164 |
Cas No.: 1628202-19-6
別名: N/A
化學名: N/A
分子式: C62H98N16O22.XC2H4O2
分子量: 1419.5
溶解度:
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Body protection compound 157 (BPC 157) is a pentadecapeptide fragment of BPC that has been found in gastric juice and has diverse biological activities.1 It increases cell migration of, and F-actin formation in, primary rat tendon fibroblasts when used at a concentration of 2 μg/ml.2 BPC 157 (0.01 and 10 μg/kg, i.p.) reduces paw swelling, bone erosion, and inflamed joint mononuclear cell infiltration in a rat model of rheumatoid arthritis induced by complete Freund's adjuvant (CFA).3 It decreases the lesion size of gastric ulcers induced by indomethacin , aspirin , or diclofenac in rats at the same doses. BCP 157 (0.01 and 10 μg/kg, i.p.) decreases the duration of catalepsy and reduces tremor severity in a mouse model of Parkinson's disease induced by MPTP.4 1.Sikiric, P., Seiwerth, S., Rucman, R., et al.Brain-gut axis and pentadecapeptide BPC 157: Theoretical and practical implicationsCurr. Neuropharmacol.14(8)857-865(2016)
2.Chang, C.-H., Tsai, W.-C., Lin, M.-S., et al.The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migrationJ. Appl. Physiol.110(3)774-780(2011)
3.Sikiric, P., Seiwerth, S., Grabarevic, Z., et al.Pentadecapeptide BPC 157 positively affects both non-steroidal anti-inflammatory agent-induced gastrointestinal lesions and adjuvant arthritis in ratsJ. Physiol. (Paris)91(3-5)113-122(1997)
4.Sikiric, P., Marovic, A., Matoz, W., et al.A behavioural study of the effect of pentadecapeptide BPC 157 in Parkinson's disease models in mice and gastric lesions induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridineJ. Physiol. (Paris)93(6)505-512(1999)
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