產品屬性：
產品名稱 | COR659 |
規格 | 10mM*1 mL in DMSO、5mg、10mg、25mg、50mg、100mg |
貨號 | EY-01Y16226 |
Cas No.: 544450-68-2
別名: N/A
化學名: N/A
分子式: C16H16ClNO3S
分子量: 337.82
溶解度: DMSO: 33.33 mg/mL (98.66 mM)
儲存條件: 4°C, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
COR659 is a GABAB positive allosteric modulator (PAM) . COR659 suppresses alcohol and chocolate self-administration in rats[1].COR659 apparently exerts its effects via a composite mechanism, including positive allosteric modulation of the GABAB receptor and an action at the cannabinoid CB1 receptor[3].COR659 (0, 2.5, 5 and 10 mg/kg) treatment is completely ineffective on lever-responding (FR10) for regular food pellets in food-deprived Wistar rats[1].COR659 is able to suppress lever-responding for a sucrose solution in sP rats and a chocolate solution in Wistar rats[2].
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