產品屬性：
產品名稱 | Deacetylforskolin |
規格 | 1 mg、5 mg |
貨號 | EY-01Y16225 |
Cas No.: 64657-20-1
別名: N/A
化學名: N/A
分子式: C20H32O6
分子量: 368.5
溶解度: Chloroform: slightly soluble,Methanol: slightly soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Deacetylforskolin is a diterpene and a derivative of forskolin that has been found in C. forskohlii and has diverse biological activities.1,2,3,4 It activates rat adipocyte adenylyl cyclase (IC50 = 20 μM) and inhibits glucose transport in rat adipocyte plasma membranes.2 Deactylforskolin (30-1,000 μg/kg) reduces blood pressure in spontaneously hypertensive rats.3 It also attenuates hypercapnia-induced impairments in the passive avoidance response in mice.41.Gabetta, B., Zini, G., and Danieli, B.Minor Diterpenoids of Coleus forskohliiPhytochemistry28(3)859-862(1989)
2.Joost, H.G., Habberfield, A.D., Simpson, I.A., et al.Activation of adenylate cyclase and inhibition of glucose transport in rat adipocytes by forskolin analogues: structural determinants for distinct sites of actionMol. Pharmacol.33(4)449-453(1988)
3.Bhat, S.V., Dohadwalla, A.N., Bajwa, B.S., et al.The antihypertensive and positive inotropic diterpene forskolin: Effects of structural modifications on its activityJ. Med. Chem.26(4)486-492(1983)
4.McCulloch, A.J., Thomson, T.A., and Deacon, R.Hypoxic amnesia and its reversal with forskolinBiochem. Soc. Trans.17(1)212-213(1988)
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