產品屬性：
產品名稱 | CAY10766 |
規格 | 1 mg、5 mg、10 mg |
貨號 | EY-01Y16416 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C17H22ClF3N2O
分子量: 362.8
溶解度: DMF: 11mg/mL,DMF:PBS (pH 7.2) (1:2): 0.3mg/mL,DMSO: 10mg/mL
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
CAY10766 is an antiviral compound.1 It inhibits entry of influenza virus-like particles pseudotyped with hemagglutinin A (HA) from H5N1 influenza A virus into A549 cells (EC50 = 0.24 μM). CAY10766 (1 μM) reduces H1N1 and H5N1 influenza A viral titers in infected MDCK cells. It also exhibits synergy with oseltamivir carboxylate in MDCK cells infected with the influenza A reporter PR8-NS1-Gluc virus.1.Gaisina, I.N., Peet, N.P., Cheng, H., et al.Optimization of 4?aminopiperidines as inhibitors of influenza A viral entry that are synergistic with oseltamivirJ. Med. Chem.63(6)312-3130(2020)
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