產品屬性:
產品名稱 | Dehydro-ZINC39395747 |
規格 | 10mM*1 mL in DMSO、5mg、10mg、50mg、100mg |
貨號 | EY-01Y16472 |
Cas No.: 433248-87-4
別名: N/A
化學名: N/A
分子式: C12H9N3O2S2

分子量: 291.35
溶解度: DMSO: 10 mg/mL (34.32 mM; ultrasonic and adjust pH to 6 with HCl)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC50 of 9.14 μM and a Kd of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells[1].[1]. Rahaman MM, et al. Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability. J Biol Chem. 2015 Jul 3;290(27):16861-72.
特別提醒公司產品僅供科研使用