產品屬性：
產品名稱 | Cefsulodin (sodium salt hydrate) |
規格 | 100mg、250mg、500mg、1g |
貨號 | EY-01Y16663 |
Cas No.: 1426397-23-0
別名: N/A
化學名: N/A
分子式: C22H19N4O8S2?Na [XH2O]
分子量: 531.5
溶解度: DMSO: 0.1 mg/ml,PBS (pH 7.2): 10 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Cefsulodin is a β-lactam antibiotic that lyses actively-growing E. coli by binding specifically to the intermembrane proteins, penicillin-binding proteins 1a and b, whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.1 Cefsulodin has been used in combination with other β-lactam antibiotics, such as cefazolin as a strategy to circumvent drug resistance.21.Jacoby, G.H., and Young, K.D.Cell cycle-independent lysis of Escherichia coli by cefsulodin, an inhibitor of penicillin-binding proteins 1a and 1bJournal of Bacteriology173(1)1-5(1991)
2.Sarkar, S.K., Dutta, M., Kumar, A., et al.Sub-inhibitory cefsulodin sensitization of E. coli to ?-lactams is mediated by PBP1b inhibitionPLoS One7(11)(2012)
特別提醒公司產品僅供科研使用
