產品屬性：
產品名稱 | 2-heptyl-3-hydroxy-4(1H)-Quinolone |
規格 | 5mg、10mg |
貨號 | EY-01Y16946 |
Cas No.: 108985-27-9
別名: PQS, Pseudomonas Quinolone Signal
化學名: 2-heptyl-3-hydroxy-4(1H)-quinolinone
分子式: C16H21NO2
分子量: 259.3
溶解度: Soluble in methanol
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
2-heptyl-3-hydroxy-4(1H)-Quinolone is a quorum-sensing signaling molecule produced by P. aeruginosa in response to increasing cell density.[1] It increases expression of the lasB gene, which encodes the virulence factor elastase, in P. aeruginosa (EC50 = ~30 μM in a reporter cell assay). 2-heptyl-3-hydroxy-4(1H)-Quinolone (60 μM) increases secretion of the metabolite pyocyanin and the lectin PA-IL, as well as increases biofilm production in P. aeruginosa populations.[2] It also reduces iron levels in P. aeruginosa growth media when used at a concentration of 40 μM and acts as an iron chelator in a Fe(III)-sulfate solution.[3]
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