產品屬性：
產品名稱 | SB-633825 |
規格 | 5mg、10mg、50mg、100mg |
貨號 | EY-01Y17074 |
Cas No.: 956613-01-7
別名: N/A
化學名: N/A
分子式: C28H25N3O3S
分子量: 483.58
溶解度: N/A
儲存條件: N/A
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis[1].SB-633825 inhibits TIE2 Tyrosine-protein kinase (TIE2), lymphocyte-oriented kinase (LOK; STK10) and breast tumor kinase (Brk; PTK6)[1]. SB-633825 inhibits LOK to 44% maximal activity and TIE2 to 75% maximal activity at 0.1 μM[1].[1]. Elkins JM, et al. Comprehensive characterization of the Published Kinase Inhibitor Set. Nat Biotechnol. 2016 Jan;34(1):95-103.
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