產品屬性：
產品名稱 | AZ-GHS-22 |
規格 | 1 mg、5 mg、10 mg |
貨號 | EY-01Y17525 |
Cas No.: 1143020-91-0
別名: N/A
化學名: N/A
分子式: C27H33ClN6O5S2
分子量: 621.2
溶解度: 0.1 M HCl: 25 mg/ml,DMSO: 50 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
AZ-GHS-22 is an inverse agonist of the growth hormone secretagogue receptor 1a (GHS-R1a), which is also known as the ghrelin receptor.1 It binds to GHS-R1a with an IC50 value of 0.77 nM. AZ-GHS-22 decreases food intake in mice by 54% in the first two hours after administration of a 100 mg/kg dose.1.McCoull, W., Barton, P., Brown, A.J.H., et al.Identification, optimization, and pharmacology of acylurea GHS-R1a inverse agonistsJ. Med. Chem.57(14)6128-6140(2014)
特別提醒公司產品僅供科研使用
